E-cigarette smoke immobilizes immune cells – study

E-cigarette smoke immobilizes immune cells – study

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Inhaling e-cigarette vapors can disrupt the normal functioning of immune cells. This is stated in a study conducted by scientists from the University of Birmingham. The findings were published in the Journal of Allergy and Clinical Immunology, writes Medical Xpress. Smoke from e-cigarettes can damage neutrophils, the cells of the first line of defense in the human immune system. The researchers took blood samples from healthy donors who had never smoked, as well as from people who use e-cigarettes (both with and without nicotine). Photo: diego_cervo/Depositphotos For the experiment, they took 40 puffs of unflavored (unflavored) vape (according to previous studies, this amount is considered a low daily exposure). Test results showed that in both the nicotine and non-nicotine groups, the neutrophils remained alive, but “stuck in place.” Because of this, they became unable to effectively resist threats to the body. “Interestingly, vapors from e-liquids that do not contain nicotine have the same negative effects as vapors from e-liquids that contain nicotine,” said Dr. Aaron Scott, professor of respiratory science and lead author of the study. The scientists also found that neutrophils after vaping had an accumulation of microfilaments (actin protein threads – ed.) inside the cells. Because these protein filaments cannot reorganize properly, normal cell function is inhibited. Actin is normally found as filaments and rearranges itself into a network to help the cell change its shape. Thanks to this feature, neutrophils can normally move towards the threat and destroy it. “Neutrophils normally protect the lungs by moving from the blood to the site of possible damage before using a number of protective functions to protect the lungs. Therefore, the observed effect of e-cigarette vapor on their mobility is of serious concern. E-cigarette smokers are at increased risk of respiratory diseases,” the professor explained. of Respiratory Medicine David Thickett. We will remind, according to the statistical data of the Ministry of Health, the prevalence of smoking in Ukraine decreased by 36% in 12 years. Read also: “Legionaires’ disease” in Poland: what are the symptoms and what do the Ministry of Health say about the risk of an outbreak in Ukraine

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