Concussions cause immediate damage that may trigger Alzheimer’s disease, study finds
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Scientists have discovered that the damage that causes Alzheimer’s disease can occur immediately after a concussion. This was reported by ScienceAlert with reference to research by the American Purdue University. In 2019, scientists have already established a link between traumatic brain injury and an increased risk of Alzheimer’s disease. Currently, Purdue researchers have found out why this happens. University scientists created a “mini brain” for the experiment. In it, along with nutrients, clusters of cultured mouse neurons were placed. “Essentially, we’ve created a miniature brain that we can hit and then study,” commented neuroscientist Riya Shi of Purdue University. Importantly! This material is based on the latest and current scientific research, is of an informational and reference nature only and cannot be the basis for establishing a medical diagnosis. To establish a diagnosis, be sure to consult a doctor! Photo: HayDmitriy/Depositphotos During the experiment, scientists hit the “mini brain” three times with a force of 200 g. Each of these hits could have caused a concussion while playing American football. During the impact, the scientists noticed a surge of acrolein, a compound associated with cell damage and neurodegenerative diseases, in the “mini brain”. “There was also an increase in misfolded amyloid beta-42 proteins, caused by an increase in acrolein. Clumps of these proteins are found in the brains of people with Alzheimer’s disease. These are two key risk signals that occur within the first 24 hours after simulated blows to the head,” he says. edition. Further tests showed that the drug hydrazalin can reduce acrolein after a concussion. It is currently used to treat high blood pressure. As reported by ScienceAlert, the “mini brain” constructed by scientists should help in the further study of Alzheimer’s disease. “With this device, people need to know that when they get a concussion, they won’t have 10 years before they see the damage. The clock starts ticking right away, and if we want to do something about it, we need to act fast,” he said. Riya Shi. We will remind you that earlier we reported that intermittent fasting can reduce the symptoms of Alzheimer’s disease. Read also: Scientists have found a connection between viral infections and the development of Parkinson’s and Alzheimer’s diseases
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