Espresso can help prevent Alzheimer’s disease – scientists
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Italian scientists have said that espresso can prevent the development of Alzheimer’s disease. Scientists at the University of Verona found that dark coffee destroys tau proteins that accumulate in the brain and kill neurons (a process thought to contribute to neurodegenerative disease). The research was published in the Journal of Agricultural and Food Chemistry, which was founded by the American Chemical Society, reports The Independent. For the experiment, the team of scientists prepared espresso from store-bought beans, and then characterized the chemical composition of the drinks. Researchers studied caffeine, trigonelline, and theobromine (alkaloids), as well as the flavonoid genistein, found in coffee. “Recent studies have shown that coffee can have a positive effect on some neurodegenerative diseases, particularly Alzheimer’s disease. Although the exact mechanisms that cause these conditions are still unclear, it is believed that tau protein plays an important role,” said the lead author. research by Mariapin D’Onofrio. Read also: Scientists found out whether morning coffee really “charges” energy Photo: jukai5/Depositphotos In healthy people, tau protein helps stabilize structures in the brain, but in neurodegenerative diseases it can form fibrils – “balls” that accumulate in areas brain responsible for memory. These formations are one of the key causes of slower thinking and memory impairment, but a recent study showed that drinking espresso prevents their formation (certain coffee components are able to prevent the aggregation, condensation and seeding activity of the tau protein). Moreover, the stronger the coffee, the shorter these fibrils were, Professor D’Onofrio explained. “Through in vitro (in vitro) and cellular experiments, we demonstrated that whole coffee extract, caffeine, and genistein have biological properties to prevent the aggregation, condensation, and seeding activity of the tau repeat region. We also identified a set of coffee compounds capable of binding with formed tau fibrils. These results deepen the understanding of the neuroprotective potential of espresso…” the article states. At the same time, the professor noted that the beneficial properties of strong coffee are preserved even in latte, Americano or even espresso-martini cocktails. “We have presented a large body of evidence that espresso is a source of natural compounds that show beneficial properties for ameliorating tau-related pathologies. Our findings may pave the way for further research in the field of developing biologically active compounds for the prevention and treatment of tau -pathology”, scientists believe. At the same time, an excessive amount of coffee can harm health. The Ministry of Health advises to consume no more than 400 mg of caffeine per day for those who do not have contraindications to this drink. It will be recalled that earlier scientists developed a drug that slows down dementia. Read also: What is the harm of coffee, what does it save from and how much is better to drink
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