In the UK, the first patients received an experimental cancer therapy
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A “revolutionary” cancer treatment known as mRNA therapy has begun to be used on patients at Hammersmith Hospital in west London. Such therapy may become a new approach to the fight against cancer.
The trials are conducted to assess the safety and effectiveness of the therapy in the treatment of melanoma, lung cancer and other solid tumors, writes The Guardian.
The new treatment uses genetic material known as mRNA. It seems to illuminate the patient’s immune system with common tumor markers. Its purpose is to help the mRNA recognize and fight cancer cells that express these markers.
“A new mRNA-based cancer immunotherapy opens the way to enlisting the patient’s own immune system to fight cancer“, said Dr. David Pinato from Imperial College London.
| PHOTO: CITAlliance/Depositphotos |
He added that this research is still in its early stages and it could be years before it becomes available to patients. However, it is an important basis from which less toxic and more precise new methods of fighting cancer could be developed.
Preclinical tests in both cell and animal models of cancer have shown that the new mRNA therapy affects the immune system and can be offered to patients in early clinical trials.
A number of cancer vaccines have recently begun clinical trials around the world. They are divided into two categories: personalized cancer immunotherapy, which is based on extracting the patient’s own genetic material from his tumor, and therapeutic cancer immunotherapy – mRNA, which is tailored to a specific type of cancer.
The main goal of the new study is to find out:
- is this type of mRNA therapy safe;
- how it is tolerated by patients with lung or skin cancer;
- whether it can shrink tumors.
We will remind you that earlier we wrote that scientists are researching a vaccine that can help in the treatment of pancreatic cancer.
Scientists have also used gene therapy to treat angioedema. People with this condition suffer from attacks of swelling that affect areas of the face, throat, intestines and limbs.
Read also: Living in the conditions of two wars: how Ukrainian cancer patients overcome double challenges
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