One course of antibiotics per year increases the risk of developing sepsis by 70% – scientists

One course of antibiotics per year increases the risk of developing sepsis by 70% – scientists

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One course of antibiotics per year increases the risk of developing sepsis by 70%. This was shown by a new study by scientists from the University of Manchester in Britain.

Every year in Great Britain, about 250,000 cases of sepsis are registered, while about 50,000 people die from this infection. This is more than from colon, breast and prostate cancer combined, writes The Telegraph.

Sepsis is popularly called “blood infection”. According to the WHO definition, sepsis is a dangerous dysfunction of internal organs caused by a dysregulation of the body’s response to infection.

Experts found that the risk of sepsis, which is fatal in about a fifth of cases, increased with the number of courses of antibiotics a person took.

Photo: Rodolfo Parulan Jr./gettyimages

Scientists analyzed 250,000 patients who developed sepsis between January 2019 and June 2022 and compared them with a group of 1.3 million people who did not have the disease.

The study found that people who took a one- or two-week course of antibiotics over a 12-month period were 70% more likely to develop sepsis than those who did not.

Patients who received two or three courses of antibiotics in a year had a 130% greater risk of developing sepsis, and for those who received antibiotics four or more times, the risk tripled.

Scientists stated that antibiotics and their “an adverse effect on the beneficial bacteria in the gut can lead to increased susceptibility to infection“.

That’s why the chief executive of the UK’s Health Safety and Security Agency, Jenny Harries, called on the public to “treat antibiotics with respect” against the background of a surge of resistant infections.

Scientists have found out what other health factors can increase the risk of developing sepsis.

For example, the risk of developing a dangerous infection for people with cancer was more than twice as high, while for patients with chronic liver disease and chronic kidney disease the risk increased threefold.

A life-threatening infection is more common in people with neurological conditions, diabetes, immunosuppressive conditions, smokers, and people who are underweight or overweight.

Scientists said that people from the most disadvantaged sections of the population have almost twice the risk of contracting sepsis.

An analysis of the number of deaths within 30 days after infection with sepsis showed that people over 80 years old and people from disadvantaged families died more often from sepsis.

Dr Ron Daniels, founder and chief executive of the UK Sepsis Trust, said that although the study found a link between “socio-economic status of a person and the disease of sepsis, and yet the disease can affect everyone without exception“.

We will remind you that there is a myth that antibiotics can be used against viral diseases or for prevention.

However, this absolutely cannot be done – doctors should prescribe antibiotics only when they are really necessary.

Read also: “In Bukovina, an HIV-infected man was imprisoned for raping his minor daughter”

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